DEVELOPMENT OF ACRIDONE DERIVATIVES: TARGETING C-MYC TRANSCRIPTION IN TRIPLE-NEGATIVE BREAST CANCER WITH INHIBITORY POTENTIAL

Development of Acridone Derivatives: Targeting c-MYC Transcription in Triple-Negative Breast Cancer with Inhibitory Potential

Breast cancer, especially the aggressive triple-negative subtype, poses a serious health threat to women.Unfortunately, effective targets are lacking, leading to a grim prognosis.Research highlights the crucial role of c-MYC overexpression in this form of cancer.Current Pullover Hoodie inhibitors targeting c-MYC focus on stabilizing its G-quadruple

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rTMS neuromodulation improves electrocortical functional measures of information processing and behavioral responses in autism

Objectives: Reports in autism spectrum disorders (ASD) of a minicolumnopathy with consequent deficits of lateral inhibition help explain observed behavioral and executive dysfunctions.We Collectibles propose that neuromodulation based on rTMS will enhance lateral inhibition through activation of inhibitory double bouquet interneurons and will be ac

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Human penile ossification: case report

CONTEXT: Ossification in the human penis is such a rare condition that only 34 histologically evident cases have previously been reported.Among several conditions that have been correlated with this problem the most frequent is Peyronie disease.In all these conditions, human penile ossification appears to be a metaplastic bone formation process.CAS

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